The Cochrane Child Health Field, whose tag line is "promoting best evidence in child health," has announced that a trials register will shortly be available.
Archives for September 2007
The PLoS Hub for Clinical Trials is live today – completing the merger of PLoS Clinical Trials with PLoS ONE. Our goal in developing Hubs is to provide a place where you, the researcher or reader, can easily reach relevant PLoS content and build on it. Think of the Hub as a gateway directly connecting you to articles that you are likely to be interested in; you can sign up to get email alerts of the most recent additions directly from the Hub.
I’ve always been uncomfortable with the notion that medical researchers simply hand down their wisdom to grateful and passive recipients – with patients seen as the most grateful and required to be the most passive. It was therefore a pleasure to be able to attend a one-day event in London entitled ‘Should Patients tell Researchers what to do? If so how?’ The meeting was organised jointly by the James Lind Alliance and the Association of Medical Research Charities.
PLoS Computational Biology launches a new series to look at the developing discipline around the world.
In the past, I used the title “PLoS ONE Release Candidate.” But with this release candidate, the Topaz framework allows multiple journal websites to use a single repository. So the release candidate isn’t specific to just PLoS ONE. Why is this important? Enabling multiple journals on one repository allows articles to be viewed across all sites accessing the repository. The interactive tools of PLoS ONE will be available for all journals hosted on Topaz. This will include articles originally published in PLoS Clinical Trials and include articles published in PLoS Neglected Tropical Diseases.
Today is my Birthday. I’m entering a prime of life, although I’m not going to tell you which one. I only mention this because PLoS ONE has given me an extra special gift. This day, my birthday as I may have mentioned, we accepted for publication our 1,000th paper.
Last week I gave a talk at the British Association for the Advancement of Science (BA) BA Festival of Science as part of a session organised by CAMARADES, a collaboration that provides a supporting framework for groups involved in the systematic review and meta-analysis of data from animal studies in experimental stroke. The basic premise of the session was that animal experiments, in stroke research at least, are not being done to the level of rigour that we have come to expect of human studies: for example sample size calculations, true randomization to experimental groups and blinding of those who assess outcomes to the experimental group are all rare. The problem is that studies that don’t adhere to such best practice are more likely to come up with positive findings. Other speakers discussed best practice in human studies, the specific problems in investigating stroke, and other perspectives on the problem. The issue I was speaking on is what journals can do here and I summarised this in two points: