At the close of the year, PLoS Medicine has published five new articles, including our monthly editorial.
Anna Nordström and Peter Nordström analyzed a prospective nationwide cohort of 440,742 Swedish men and find that reduced cognitive function in young adulthood is associated with increased risk of subdural hematoma later in life, whereas a higher level of education and physical fitness is associated with a decreased risk.
Seena Fazel and colleagues conducted a longitudinal follow-up study in Sweden that evaluated the risks of violent crime subsequent to hospitalization for epilepsy or traumatic brain injury; their findings call into question an association between epilepsy and violent crime, although there may be a relationship between traumatic brain injury and violent crime. Jan Volavka provides a Perspective on the article.
Rafael Dal-Ré and colleagues argue that the recruitment targets and performance of all site investigators in multi-centre clinical trials should be disclosed in trial registration sites before a trial starts, and when it ends.