A leader in the field of post-publication peer-review, Faculty of 1000, has ranked one-hundred and twenty PLoS ONE articles as being among the most important published in biology and medicine publications during 2010. You can check out the full list here* or read the top five F1000 ranked below.
- A conserved behavioral state barrier impedes transitions between anesthetic-induced unconsciousness and wakefulness: evidence for neural inertia. Friedman EB, et al. PLoS ONE. 2010; 5(7):e11903.
F1000 article factor (FFa): 15 - From sea to sea: Canada’s three oceans of biodiversity. Archambault P, et al. PLoS ONE. 2010; 5(8):e12182
F1000 article factor (FFa): 10 - Do seasons have an influence on the incidence of depression? The use of an internet search engine query data as a proxy of human affect. Yang AC, Huang NE, Peng CK, Tsai SJ. PLoS ONE. 2010; 5(10):e13728
F1000 article factor (FFa): 10 - Coordinated progression through two subtranscriptomes underlies the tachyzoite cycle of Toxoplasma gondii. Behnke MS, et al. PLoS ONE. 2010; 5(8):e12354
F1000 article factor (FFa): 10 - The protease inhibitor alpha-2-macroglobulin-like-1 is the p170 antigen recognized by paraneoplastic pemphigus autoantibodies in human. Schepens I, et al. PLoS ONE. 2010; 5(8):e12250
F1000 article factor (FFa): 10
* Faculty of 1000 is a subscription-based service. You can access the rankings free of charge but will need a subscription to view the Faculty comments on all papers.



How does that compare, in absolute terms and relative to total number of papers published in the same year, with other journals?
We will publish 6,800 articles this year, so it is 120/6,800 = 2% (approx). It isn’t clear what you would consider to be a competitive title, but for example PNAS appears to have about 460 evaluations in F1000 this year.
Thanks for the extra data! Good point about appropriate comparison journals being hard to choose.