The Washington Post recently reported that the United States’ Food and Drug Administration (FDA) plans to limit the amount of sodium allowed in processed foods, following recommendations from the Institute of Medicine made in their report, “Strategies to Reduce Sodium Intake in the United States“. Their article claims that the FDA and U.S. Department of Agriculture are joining forces over the next ten years in order to enact this initiative, which they say will limit health risks from hypertension and heart disease, among other illnesses.
The FDA issued a response on April 20th, stating that while they support the reduction of sodium used in the preparation of food, they have not yet put any laws or regulations into effect. They say that before any regulations are enacted, they will solicit feedback from both the food industry and consumers, and that it will take years before any permanent restrictions are made.
Regardless of the outcome of this debate, we know for certain that hypertension is a condition that affects one in three American adults, and that high sodium intake has been linked to cardiovascular disease.
Hypertension research has broad implications for world health trends. PLoS ONE has published many studies on various aspects of hypertension, spanning the subject areas of Genetics and Genomics, Diabetes and Endocrinology, Public Health and Epidemiology, Mental Health, and even Evolutionary Biology. Below, you’ll find a selection of some of our most highly accessed hypertension research articles (based on Article Level Metrics).
Feel free to share these research articles with colleagues and let them know that we welcome more submissions in this area!
Top-Down Lipidomics Reveals Ether Lipid Deficiency in Blood Plasma of Hypertensive Patients by Graessler J et al. (Editor: Jose A. L. Calbet, University of Las Palmas de Gran Canaria, Spain)
Polymorphisms in the WNK1 Gene Are Associated with Blood Pressure Variation and Urinary Potassium Excretion by Newhouse S et al. (Editor: Florian Kronenberg, Innsbruck Medical University, Austria)
Potential Relevance of α1-Adrenergic Receptor Autoantibodies in Refractory Hypertension by Wenzel K et al. (Editor: Timothy Secomb, University of Arizona, United States of America)
Admixture Mapping Provides Evidence of Association of the VNN1 Gene with Hypertension by Zhu X et al. (Editor: Greg Gibson, North Carolina State University, United States of America)
Factors Associated with Adherence to Anti-Hypertensive Treatment in Pakistan by Hashmi SK et al. (Editor: Bernhard Baune, James Cook University, Australia)
Targeting 160 Candidate Genes for Blood Pressure Regulation with a Genome-Wide Genotyping Array by Sõber S et al. (Editor: Andreas Reif, University of Wuerzburg, Germany)
Established Risk Factors Account for Most of the Racial Differences in Cardiovascular Disease Mortality by Henderson SO et al. (Editor: J. Jaime Miranda, London School of Hygiene and Tropical Medicine, Peru)
Polymorphism in NEDD4L Is Associated with Increased Salt Sensitivity, Reduced Levels of P-renin and Increased Levels of Nt-proANP by Dahlberg J et al. (Editor: Jean Carr, Institute of Human Virology, United States of America)
The M235T Polymorphism in the AGT Gene and CHD Risk: Evidence of a Hardy-Weinberg Equilibrium Violation and Publication Bias in a Meta-Analysis by Zafarmand MH et al. (Editor: Florian Kronenberg, Innsbruck Medical University, Austria)
Genetic Ancestry, Social Classification, and Racial Inequalities in Blood Pressure in Southeastern Puerto Rico by Gravlee CC et al. (Editor: Lyle Konigsberg, University of Illinois at Champaign-Urbana, United States of America)