The Editorial team at PLOS Biology believes strongly that we are Open for a Reason; precisely so that research in areas of high importance reaches the widest audience. Cancer research is one such area that should be as openly available, with associated data mineable and reusable, ideally in an open access, CC-BY journal as quickly as possible. Open access ensures the most expedient, economic and practical route to discovery and to developing potential therapeutic advances for the suite of diseases and conditions that we tend to over-simplify and apply one name to, cancer.
PLOS Biology is open for cancer research, and to highlight some of the discoveries we’ve published in this broad field, we’ve gathered together some research articles that cover various aspects of cancer biology published in PLOS Biology over the last few years, so if you’re interested in learning more about some of this great research take a look:
‘Nonheritable Cellular Variability Accelerates the Evolutionary Processes of Cancer.
Frank SA, Rosner MR (2012)
PLOS Biol 10(4): e1001296. doi:10.1371/journal.pbio.1001296
‘Cancer: The Whole Story.’
Frank SA (2011)
PLOS Biol 9(4): e1001044. doi:10.1371/journal.pbio.1001044
‘Cancer Courts Immune Response to Aid Growth.’
Mejia R (2010)
PLOS Biol 8(12): e1001004. doi:10.1371/journal.pbio.1001004
And Corresponding Research Article:
‘Live Imaging of Innate Immune Cell Sensing of Transformed Cells in Zebrafish Larvae: Parallels between Tumor Initiation and Wound Inflammation.’
Feng Y, Santoriello C, Mione M, Hurlstone A, Martin P (2010)
PLOS Biol 8(12): e1000562. doi:10.1371/journal.pbio.1000562
‘ELF5 Suppresses Estrogen Sensitivity and Underpins the Acquisition of Antiestrogen Resistance in Luminal Breast Cancer.’
Kalyuga M, Gallego-Ortega D, Lee HJ, Roden DL, Cowley MJ, et al. (2012)
PLOS Biol 10(12): e1001461. doi:10.1371/journal.pbio.1001461
‘Stimulation of Host Bone Marrow Stromal Cells by Sympathetic Nerves Promotes Breast Cancer Bone Metastasis in Mice.’
Citation: Campbell JP, Karolak MR, Ma Y, Perrien DS, Masood-Campbell SK, et al. (2012) PLOS Biol 10(7): e1001363. doi:10.1371/journal.pbio.1001363
‘Novel Role of NOX in Supporting Aerobic Glycolysis in Cancer Cells with Mitochondrial Dysfunction and as a Potential Target for Cancer Therapy.’
Lu W, Hu Y, Chen G, Chen Z, Zhang H, et al. (2012)
PLOS Biol 10(5): e1001326. doi:10.1371/journal.pbio.1001326
‘ESRRA-C11orf20 Is a Recurrent Gene Fusion in Serous Ovarian Carcinoma.’
Citation: Salzman J, Marinelli RJ, Wang PL, Green AE, Nielsen JS, et al. (2011)
PLOS Biol 9(9): e1001156. doi:10.1371/journal.pbio.1001156
‘Mesenchymal Transition and Dissemination of Cancer Cells Is Driven by Myeloid-Derived Suppressor Cells Infiltrating the Primary Tumor.’
Toh B, Wang X, Keeble J, Sim WJ, Khoo K, et al. (2011)
PLOS Biol 9(9): e1001162. doi:10.1371/journal.pbio.1001162
‘HER2 Phosphorylation Is Maintained by a PKB Negative Feedback Loop in Response to Anti-HER2 Herceptin in Breast Cancer.’
Gijsen M, King P, Perera T, Parker PJ, Harris AL, et al. (2010)
PLOS Biol 8(12): e1000563. doi:10.1371/journal.pbio.1000563
‘Targeting A20 Decreases Glioma Stem Cell Survival and Tumor Growth.’
Hjelmeland AB, Wu Q, Wickman S, Eyler C, Heddleston J, et al. (2010)
PLOS Biol 8(2): e1000319. doi:10.1371/journal.pbio.1000319
If you visit the PLOS booth (booth #544) at the AACR Annual Meeting 2013, you can collect a printed version of this collection. We hope that you will enjoy these research and magazine articles from PLOS Biology; as with all of our content they are Open Access and freely available to all.
We encourage you to consider PLOS Biology as a high visibility venue for your future research. We are interested in all areas of cancer research traversing the bedside-to-bench spectrum, and we welcome translational studies. Our editorial model involves a partnership between professional and academic editors that guarantees our authors the best of both worlds; editorial expertise from the in-house team combined with the up-to-date specialised scientific knowledge of your colleagues who serve on our editorial board.
We hope you find this collection interesting. For more information about PLOS Biology and to submit your research, please visit www.plosbiology.org.